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The Eon standard
High Purity Guarantee
Your results are only as good as your compound. Every lot of Thymosin Alpha-1 is tested by an independent ISO/IEC 17025-accredited lab in the USA. 99%+ purity isn't a target here. It's the requirement. Don't take our word for it: test any vial at an accredited lab of your choice. If HPLC purity comes back under 99%, we refund your order and pay for the test.
Size
10mg
Purity
99%+ by HPLC · guaranteed
Identity
Confirmed by mass spec
Lab
Accurate Test Labs · ISO/IEC 17025
About this compound
Thymosin Alpha-1 is a peptide made of 28 amino acids. It was first isolated from the thymus, an organ where immune cells mature. It occurs naturally as a fragment of a larger protein called prothymosin alpha. Research has measured how immune cells respond to it, including T cell development and the signals dendritic cells send.
The numbers that define Thymosin Alpha-1 and how it is being studied. For laboratory research use only.
28
Amino Acid Sequence
Acetylated thymic peptide
TLR9
Signaling Receptor
Primes dendritic cells through TLR9 and MyD88
<3 hr
Plasma Half-Life
Terminal half-life, cleared by the kidney
4
Research Areas
T-Cell Research
Viral-Response Models
Tumour-Immunity Models
How It Works
How Thymosin Alpha-1 works
The pathways Thymosin Alpha-1 acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
Thymic Immune Modulation
T-Cell Maturation
T-lymphocyte maturation and differentiation, and the balance of T-cell subsets, are measured in preclinical immunology models following Thymosin Alpha-1.
T-cell differentiation measured
Modulates CD4+/CD8+ balance
Lymphocyte counts measured in immunosuppressed models
Toll-Like Receptor Activation
TLR Signaling
Research indicates Tα1 signals through Toll-like receptors (notably TLR2 and TLR9) on dendritic cells and monocytes, influencing innate-immune activation and cytokine expression.
Engages TLR2 / TLR9 pathways
Dendritic-cell maturation
Modulates cytokine profiles
NK & Th1 Cytokine Modulation
Cytokine / NK
In-vitro and animal studies report raised natural-killer-cell activity and a shift toward a Th1 cytokine profile (IFN-γ, IL-2) - endpoints used in antiviral and antitumour immune-response research.
NK-cell activity measured
Th1 cytokine shift (IFN-γ, IL-2)
Studied in viral and tumour models
Uses & Applications
What Thymosin Alpha-1 is researched for
The main areas Thymosin Alpha-1 is being studied for - and the study-reported figures behind them.
Immunology
T-Cell Research
Used to study thymic-dependent T-lymphocyte maturation and immune cell repopulation in immunosuppressed animal models.
Antiviral
Viral-Response Models
Investigated in hepatitis and other viral models for its influence on innate and adaptive antiviral immunity.
Oncology (preclinical)
Tumour-Immunity Models
Studied as an immune adjuvant in preclinical tumour models, with NK and cytotoxic T-cell responses as the measured endpoints.
Inflammation
Cytokine Regulation
Examined for modulation of inflammatory cytokine networks and dendritic-cell function in vitro.
Study-reported magnitudes
Representative figures from published research. Bars fill as you scroll.
T-Cell Proliferation (in vitro)58%
NK-Cell Activity (vs control)74%
IFN-γ / IL-2 Expression2.2×
Dendritic-Cell Maturation63%
Figures are representative of published research findings and shown for reference.
Molecular Structure
The Thymosin Alpha-1 molecule
An interactive 3D model rendered from the compound record - rotate and explore its structure.
C129H215N33O55
Molecular formula
C129H215N33O55
Molecular weight
3108.29 g/mol
Sequence length
28 residues
CAS / ID
62304-98-7
Physical form
Lyophilized Powder
Documented purity
≥99% by HPLC
Compound Information
Full specification
Strength
10mg
Molecular Formula
C129H215N33O55
Molecular Weight
3108.29 g/mol
Purity
>99% (HPLC)
Form
Lyophilized Powder
Verified Purity
>99%
Quantity
10mg
Appearance
White to off-white powder
Stability
24 months from manufacture date when stored properly
Storage
Store at -20°C, protected from light
FAQ
Common questions about Thymosin Alpha-1
Thymosin Alpha-1 (Tα1) is an acetylated 28-amino-acid peptide originally isolated from thymic tissue (thymosin fraction 5). It is a well-characterized immunomodulator studied for its effects on T-cell maturation, Toll-like-receptor signaling, and innate/adaptive immune balance in cell-culture and animal models.
No. Thymosin Alpha-1 is not approved by the FDA for any use in the United States. A synthetic form (thymalfasin) is approved as an immunomodulator in a number of other countries, but this product is supplied strictly as a reference compound for in-vitro laboratory research.
Store the lyophilized powder at −20°C, protected from light; it is stable for approximately 24 months from manufacture. This is storage guidance for the researcher, not a shipping requirement.
Each lot is ≥99% pure by HPLC with identity confirmed by mass spectrometry and ships with third-party analytical documentation of purity, net peptide content, and endotoxin screening.
Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
