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The Eon standard
High Purity Guarantee
Your results are only as good as your compound. Every lot of DSIP is tested by an independent ISO/IEC 17025-accredited lab in the USA. 99%+ purity isn't a target here. It's the requirement. Don't take our word for it: test any vial at an accredited lab of your choice. If HPLC purity comes back under 99%, we refund your order and pay for the test.
Size
10mg
Purity
99%+ by HPLC · guaranteed
Identity
Confirmed by mass spec
Lab
Accurate Test Labs · ISO/IEC 17025
About this compound
DSIP stands for delta sleep-inducing peptide. It is nine amino acids long and was first isolated in 1977 from blood drawn during deep sleep. Studies have measured brain wave patterns, sleep timing, and stress hormone response. After nearly fifty years of research, no one has identified which receptor it binds. The mechanism is still an open question.
The numbers that define DSIP and how it is being studied. For laboratory research use only.
9
Amino Acids
Nonapeptide (WAGGDASGE)
1978
Year Sequenced
Nine-residue sequence established and synthesized
Endogenous
Origin
Naturally occurring neuropeptide
8.2%
Intact After Two Hours
In a human intestinal cell monolayer
How It Works
How DSIP works
The pathways DSIP acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
Neurotransmitter Modulation
Neuromodulator
DSIP has been reported to influence serotonin (5-HT), glutamate, dopamine and melatonin signaling - pathways tied to sleep onset and circadian timing.
Sleep Architecture
Delta Sleep ↑
Early studies associate DSIP with greater slow-wave (delta) sleep, shorter sleep onset and higher sleep efficiency, distinct from sedative-hypnotic mechanisms.
Stress & Neuroprotection
Neuroprotective
Investigated for adaptation of the stress (HPA) axis and for neuronal oxidative-stress endpoints in neurodegeneration and stroke models.
Uses & Applications
What DSIP is researched for
The main areas DSIP is being studied for - and the study-reported figures behind them.
Sleep Research
Sleep Architecture
Studied for effects on slow-wave sleep, sleep efficiency and onset latency in animal and human models.
Stress & Endocrine
Stress Adaptation
Investigated for modulation of the HPA axis and stress-response regulation.
Neuroscience
Neuroprotection
Explored for antioxidant/neuroprotective effects in models of neurodegeneration and ischemic injury.
Study-reported magnitudes
Representative figures from published research. Bars fill as you scroll.
Sleep Duration vs Placebo (130-min window)+59%
Slow-Wave (Delta) Sleepmeasured
Sleep Onset Latencymeasured
Figures are representative of published research findings and shown for reference.
Molecular Structure
The DSIP molecule
An interactive 3D model rendered from the compound record - rotate and explore its structure.
24 months from manufacture date when stored properly
Storage
Store at -20°C, protected from light
FAQ
Common questions about DSIP
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated in the 1970s from the cerebral venous blood of rabbits in an induced sleep state, studied as an endogenous modulator of sleep and stress.
Yes. DSIP is an endogenous neuropeptide found in the brain, hypothalamus and other tissues, which is part of why it is of interest as a physiological sleep regulator.
Primarily sleep regulation, but also stress adaptation, neuroprotection, chronic-pain models and studies of opioid/alcohol withdrawal.
Supplied as a lyophilized powder; store at -20°C, protected from light and moisture. Research use only.
Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
