EON RESEARCH LIBRARY // Article

Choosing between average and monoisotopic mass labels

Average and monoisotopic mass use different conventions. Comparing the numbers without their labels can make a consistent record appear contradictory.

For research use only. Not for human or veterinary use.

Before correcting a mass field, check the chemical form, isotope convention and whether the value describes a neutral entity or an ion. Retain the source precision and quantity name. A normalized database should document its chosen convention.

Reading checklist

Identify the mass convention
Check entity and charge assumptions
Document any normalization rule

Reference: Exact mass and average mass.

Sources and further reading

IUPAC: exact mass

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